Hypoxemia, oxygen content, and the regulation of cerebral blood flow
نویسندگان
چکیده
منابع مشابه
Hypoxemia, oxygen content, and the regulation of cerebral blood flow.
This review highlights the influence of oxygen (O2) availability on cerebral blood flow (CBF). Evidence for reductions in O2 content (CaO2 ) rather than arterial O2 tension (PaO2 ) as the chief regulator of cerebral vasodilation, with deoxyhemoglobin as the primary O2 sensor and upstream response effector, is discussed. We review in vitro and in vivo data to summarize the molecular mechanisms u...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
سال: 2016
ISSN: 0363-6119,1522-1490
DOI: 10.1152/ajpregu.00270.2015